If Windows Defender is interfering with the running and operation of a software installer or general use software, do the following:

1. Go to Active Directory
2. Go to NCSU > TEX > Computer Groups > TEX-Enable SmartScreen Warn and Allow Bypass
3. Add the device as a member of TEX-Enable SmartScreen Warn and Allow Bypass
4. Restart device
5. Wait 5 minutes
6. Sign in and attempt to run software again

Once software is installed, remove the device from the TEX-Enable SmartScreen Warn and Allow Bypass OU.